Osteoarthritis (OA)
Need For Early Diagnosis Video Transcript
B. Duncan X. Lascelles
BSc, BVSc, PhD, FRCVS, CertVA, DSAS(ST), DECVS, DACVS
“The reality at the moment is that despite the fact that osteoarthritis is a young dog disease, we are diagnosing it much
later on in life. In fact, I believe over half of all osteoarthritis cases are diagnosed in dogs between the ages of 8 and
about 12 to 13.
So we’re diagnosing it far too late. The destruction of the joint, the destruction of the organ of the joint has already
occurred. The pain as a disease has already set in.”
Denis J. Marcellin-Little
DEDV, DACVS, DECVS, DACVSMR
“There is tremendous benefit in diagnosing osteoarthritis earlier. Like most medical problems, we do a much better job
treating them when we become aware of them before end-stage, before they become very severe.
Diagnosing the problem early will let us implement a lot of different strategies that are going to modulate the problem
over a long period of time. We’ll be able to treat the problem in simpler ways, in less aggressive ways, in safer ways, in
smarter ways. We’ll have the opportunity to educate the owner or so over time.”
Kristin Kirkby Shaw
DVM, MS, PhD, CCRT, DACVS, DACVSMR
“If you as a veterinarian can identify dogs at risk of developing osteoarthritis, you get the opportunity to change this
dog’s entire life.
You can have powerful conversations with this client and really change the whole course of this dog’s life, keeping
them active for a very, very long period of time.”
Julia Tomlinson
BVSc, MS, PhD, DACVS, CCRP, CVSMT, DACVSMR
“Early diagnosis is really going to help the management to try and keep the patient as active in life and as comfortably active in life as long as possible, which is also going to feed into helping reduce obesity and happiness of the client-dog companionship.”
Bryan T. Torres
DVM, PhD, DACVS-SA, DACVSMR
“One of the huge benefits about being able to identify something like osteoarthritis early is we really improve our chances of maintaining quality of life, maintaining joint function, maintaining the patient, the animal, the dog’s ability to do the things that they love to do for as long as possible. And that really is something that we should all strive to do.”
Whit Cothern
DVM
“We all know that if we can diagnose and begin management of that disease process at a younger age, that it’s a much more successful outcome for all parties involved: the pet, the pet owner, and the veterinarian.”
The participants are paid consultants for American Regent Animal Health. The opinions of these consultants may not be representative of American Regent Animal Health.
© 2021, American Regent, Inc.
NP-AC-US-0033 11/2020
Osteoarthritis (OA)
Multimodal Approach Video Transcript
David L. Dycus DVM, MS, CCRP, DACVS-SA
“There are many other avenues of things we can use from a management tool, whether it’s intraarticular injections,
whether it’s the usage of Adequan® Canine, whether it’s the usage of formal physical rehabilitation...
“...or other things, using them together, with the whole goal being to preserve the life of the joint by keeping the dog as
absolutely comfortable as possible, to maintain a great quality of life, and to maintain that strength of the human-animal
bond.”
Kristin Kirkby Shaw
DVM, MS, PhD, CCRT, DACVS, DACVSMR
“I think there’s a misconception among dog owners and veterinarians that dogs with osteoarthritis shouldn’t be active,
that anytime they bend their joints it’s uncomfortable for them. And really, it’s quite the opposite.
“We need to keep those joints moving, whether it is through manual therapy with a physical therapist or a rehab vet or
it’s just having the dog do a series of exercises at home, sit to stand, shake and high five, some really basic things that can
help keep the muscles strong and those joints limber and ultimately change how that dog functions in their life.”
Bryan T. Torres
DVM, PhD, DACVS-SA, DACVSMR
“So when I think about how I manage osteoarthritis in my patients, there are many things that I use...
“...we see these patients later in life, they’re having trouble, they’re having a lameness. They’re sore.
They’re not able to do the things that they want to do, and we end up treating them with these medications or these
nutraceuticals, these nonsteroidals, surgery, other things like that. Something like Adequan® Canine can be very
beneficial in these patients as well. It also can be highly beneficial early on in the disease process.”
The participants are paid consultants for American Regent Animal Health. The opinions of these consultants may not be representative of American Regent Animal Health.
© 2021, American Regent, Inc.
PP-AC-US-0309 11/2020
Osteoarthritis (OA)
Not Just An Old Dog Disease Video Transcript
Mark E. Epstein
DVM, DABVP (C/F), CVPP
“If a dog has hip dysplasia, they were born with hip dysplasia. So even as puppies, that pathophysiology is beginning.
Even if they’re not symptomatic, they have the OA and we need to kind of fill that, find those patients.
We need to fill that void in there and then catch it also when it’s just beginning to be symptomatic, when we can educate
pet owners when to recognize those earliest parts.”
B. Duncan X. Lascelles
BSc, BVSc, PhD, FRCVS, CertVA, DSAS(ST), DECVS, DACVS
“So, these young puppies have developmental disease that is driving, initiating osteoarthritis.
“... I think it’s incumbent upon us to try and make the diagnosis of that disease earlier. If we can do that, I think we can
improve the future for those dogs.”
Kristin Kirkby Shaw
DVM, MS, PhD, CCRT, DACVS, DACVSMR
“I think that osteoarthritis is truly a disease that starts in young dogs.
“It’s almost always more often identified in older dogs, but the young dogs that have a risk factor for developing
osteoarthritis are truly the ones that we should be identifying but are most commonly the ones that are being missed.”
The participants are paid consultants for American Regent Animal Health. The opinions of these consultants may not be representative of American Regent Animal Health.
© 2021, American Regent, Inc.
NP-NA-US-0342 11/2020
Osteoarthritis (OA)
Treating Early With Adequan® Canine (polysulfated glycosaminoglycan) Video Transcript
Denis J. Marcellin-Little
DEDV, DACVS, DECVS, DACVSMR
“We can positively impact osteoarthritis at its early stages by protecting cartilage. For example, with Adequan® Canine,
we know that cartilage breakdown can be decreased, the cartilage can be protected early in the course of the disease.
“This has a profound positive impact on dogs because we catch the disease at its early stages. We will have healthier
joints for a lifetime.”
Kristin Kirkby Shaw
DVM, MS, PhD, CCRT, DACVS, DACVSMR
“There are certain activities that are better and certain ones that are worse. And then there are some products and some treatments that we can start using earlier on in the osteoarthritis disease process
that can really potentially change the whole course of the disease, and they’re going to be most effective early on.
“And most specifically I’m talking about Adequan® Canine.”
Julia Tomlinson
BVSc, MS, PhD, DACVS, CCRP, CVSMT, DACVSMR
“In my practice Adequan® Canine is one of my initial go-to medications for early osteoarthritis. I really feel that we can
intervene to try and help the joint health a little bit more than we can with some of the other things available to me.
“And I like to be able to minimize the use of nonsteroidals when we’re early in the disease so that we can use it as maybe a rescue medication and use Adequan® Canine more.”
Bryan T. Torres
DVM, PhD, DACVS-SA, DACVSMR
“When it comes to something like osteoarthritis, treating it early is the way to go. This is with any disease process, right?
“And so something like Adequan® Canine that we can use early on when we first diagnose osteoarthritis in a patient,
and we can do that, then make an impact for a long period of time with them can be highly beneficial.”
Whit Cothern
DVM
“We want to have that early discussion about the use of Adequan® Canine, have that out there as one of the therapeutic options, a very important therapeutic option, early in our osteoarthritis management protocols.”
Anne Dagner
DVM
“The first thing I tell clients about Adequan® Canine and why it could be right for their dog is that we really want to slow
the progression of osteoarthritis. And that’s what the main goal is when we’re using this drug.
“The next thing I talk to them about is that it’s been around, it’s been approved by the FDA so that we know it’s a safe and
effective product. So we feel confident when we’re using it in their dog.”
The participants are paid consultants for American Regent Animal Health. The opinions of these consultants may not be representative of American Regent Animal Health.
© 2021, American Regent, Inc.
PP-AC-US-0310 11/2020
Osteoarthritis (OA)
Benefits of Adequan® Canine (polysulfated glycosaminglycan) Video Transcript
Mark E. Epstein
DVM, DABVP (C/F), CVPP
“Adequan® Canine has a couple of a really important advantages over any other type of product or therapeutic that you
might be thinking about for joints...
“...and chief among them are that it has data behind it. It has good data behind it in terms of being able to kind of keep
the cartilage from degrading any faster than it otherwise should. And further, it’s FDA approved.”
Denis J. Marcellin-Little
DEDV, DACVS, DECVS, DACVSMR
“Adequan® Canine is remarkable because of its ability to protect the cartilage of dogs that are developing osteoarthritis.
“It’s able to protect cartilage from degeneration, and we don’t have that type of information about other things that we
use in managing osteoarthritis in dogs.”
Kristin Kirkby Shaw
DVM, MS, PhD, CCRT, DACVS, DACVSMR
“In my practice, I talk about Adequan® Canine with almost every patient because I feel like it’s such an important
component of a comprehensive osteoarthritis plan.
“There’s really nothing else out there quite like it.”
Bryan T. Torres
DVM, PhD, DACVS-SA, DACVSMR
“When we think about osteoarthritis, we think about these two concepts of identifying and treating early and treating
the symptoms later on.
“The benefit of Adequan® Canine is that we can use it early on in the disease process and treat these animals and make a
lasting impact.”
Whit Cothern
DVM
“Adequan® Canine provides us a unique opportunity to better control the disease progression of OA with the pet owner.
The fact that this is injectable does help that process, but it also is a product that allows you to practice real medicine.
“You become, again, that trusted valuable resource to the pet owner, and they want to come to you to discuss OA and
OA progression in their pet.”
Anne Dagner
DVM
“When I have a dog that needs Adequan® Canine, and I’m trying to talk to the client about why this drug is the right thing
for their dog, we start by talking about how the drug works.
“We talk about delaying the progression of osteoarthritis. We talk about the proven track record. We talk about Adequan®
Canine being an FDA-approved product, so we have confidence in it using it in their patient.”
The participants are paid consultants for American Regent Animal Health. The opinions of these consultants may not be representative of American Regent Animal Health.
© 2021, American Regent, Inc.
PP-AC-US-0311 11/2020
Osteoarthritis (OA)
Need To Treat Early Video Transcript
Mark E. Epstein
DVM, DABVP (C/F), CVPP
“...we only have a certain amount of capital of time and attention from the owner. So it does make it a significant
challenge.
“My guidance would be that with any inclination of a COAST one or a two dog, that if you can make sure that the subject
is brought forward, it is introduced to the client at that point, then you will have gone a step further than probably you
otherwise would have. If we can move the profession that far, that’s an important step to take.”
Denis J. Marcellin-Little
DEDV, DACVS, DECVS, DACVSMR
“It is in the patients, the owners, and our best interests to manage osteoarthritis from its early stages, not from its late
stages.”
Julia Tomlinson
BVSc, MS, PhD, DACVS, CCRP, CVSMT, DACVSMR
“If we start treating very late in the disease, then we’re really just trying to play catch up. We’ve already lost some
motion in the joint so you have some stiffness that’s going to factor in and feed into pain and inactivity, which again is
going to feed into other problems in practice such as obesity.”
The participants are paid consultants for American Regent Animal Health. The opinions of these consultants may not be representative of American Regent Animal Health.
© 2021, American Regent, Inc.
NP-NA-US-0344 11/2020
Osteoarthritis (OA)
Getting Pet Owner Involved Video Transcript
Denis J. Marcellin-Little
DEDV, DACVS, DECVS, DACVSMR
“We’ve got to be very sensitive to what the owner sees at home. Even if the owner is not that concerned about what they
see, we’ve got to probe them. We’ve got to ask them what’s going on at home, and we’ve got to never dismiss as a
clinician some red flags that the owner will bring up.
“An unusual limb position, an unusual way to sleep, an unusual posture or gait most often is going to be the
consequence of a painful joint that may not be diagnosed yet.”
David L. Dycus
DVM, MS, CCRP, DACVS-SA
“We want to let them know on the front end this is the expectations and these are the things that we can do to hopefully
prevent in some situations,
“...or at least dramatically slow down the progression, so that they may never have clinical signs that we need to manage
pharmaceutically or from other options.”
Kristin Kirkby Shaw
DVM, MS, PhD, CCRT, DACVS, DACVSMR
“While osteoarthritis is a potentially debilitating disease, it doesn’t always have to be, and it doesn’t have to be a scary
word. We need to frame it in a positive sense and a hopeful sense and give clients the tools to help their own dog.
“And ultimately we, as veterinarians, are the advocate for the dog. And by not having these tough conversations with the
client, we’re not doing our job.”
Whit Cothern
DVM
“Having these conversations about osteoarthritis, especially in these higher risk breeds, with the pet owner is vitally
important.
“We want to loop them in on the therapies that are available. We want to have the discussions about nutrition and
weight management and breed predilections.”
The participants are paid consultants for American Regent Animal Health. The opinions of these consultants may not be representative of American Regent Animal Health.
© 2021, American Regent, Inc.
NP-NA-US-0343 11/2020