Disease-modifying osteoarthritis drugs (DMOADs) are drugs that act on the tissues involved in canine osteoarthritis (OA) to prevent the progression of structural changes.1 Adequan Canine is the only FDA-approved DMOAD. It is proven safe and effective in helping restore joint lubrication and renewing the building blocks of healthy cartilage, so it can be most effective. effective when used early in the arthritis disease process when there’s still time to slow down cartilage degradation.2
No.
No, there is no generic version of Adequan Canine. Like their brand-name equivalents, generic drugs must be approved by the FDA. Some canine joint supplements and medical devices are named similarly to the active ingredient in Adequan Canine, but can't make claims to achieve similar results. These products are not equivalent to Adequan Canine. They are not backed by the required scientific testing to be approved by the FDA as a generic drug. As an FDA-approved pharmaceutical product, Adequan Canine has gone through a rigorous scientific approval process and must also be made in a facility that adheres to Good Manufacturing Practices.
Watch how Adequan Canine works. Check out the MOA video.
Adequan Canine is supplied as 100 mg/mL in a 5 mL preserved multiple dose vial. Each package contains 2 vials.
The approved label dose of Adequan Canine is 2 mg/lb body weight (0.02 mL/lb or 1 mL per 50 lb) by intramuscular injection only, twice weekly for up to 4 weeks (maximum of 8 injections). Adequan Canine is indicated for the control of the clinical signs of OA, and may be used as needed when clinical signs reoccur.
Intramuscular (IM) administration should be in a major muscle group.
No, there has been no stability testing of Adequan Canine when stored in a syringe and this is not recommended. Each dose should be drawn into a syringe and used immediately.
No, Adequan Canine needs to be stored at 68° to 77° F (20° to 25° C) with excursions permitted to 59° to 86° F (15° to 30° C). Avoid prolonged exposure to temperatures greater or equal to 104° F (40° C).
Yes, Adequan Canine contains a preservative, which allows for multiple punctures of an individual vial. Adequan Canine must be used within 28 days of first puncture and is limited to a maximum puncture of 10 times. Please properly dispose of spent needles in accordance with all federal, state and local environmental laws.
No, syringes are not included with Adequan Canine.
There are no age or breed restrictions.
Adequan Canine has not been evaluated for use with other drugs. There are no specific drug contraindications and Adequan Canine may be used as part of a multimodal approach for the management of canine osteoarthritis.
Do not use in dogs showing a hypersensitivity to polysulfated glycosaminoglycan. PSGAG is a synthetic heparinoid; do not use in dogs with known or suspected bleeding disorders.
The safe use of Adequan Canine used in breeding, pregnant or lactating dogs has not been evaluated. Use with caution in dogs with renal or hepatic impairment.
Adequan® Canine should not be used in dogs who are hypersensitive to polysulfated glycosaminoglycan (PSGAG) or who have a known or suspected bleeding disorder. It should be used with caution in dogs with renal or hepatic impairment. Adverse reactions in clinical studies (transient pain at injection site, transient diarrhea, and abnormal bleeding) were mild and self-limiting. In post approval experience, death has been reported in some cases; vomiting, anorexia, depression/ lethargy and diarrhea have also been reported. The safe use of PSGAG in breeding, pregnant or lactating dogs has not been evaluated. CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian. For additional safety information, please see the Full Prescribing Information.
Adequan Canine can be ordered through a wide network of authorized veterinary distributors. Please visit Ordering Information or call American Regent Animal Health at 800-458-0163.
Contact your distributor.
Short-dated or expired Adequan Canine product should be returned to the distributor that originally supplied the product, per their established return policies. Contact your distributor or American Regent Animal Health at 800-458-0163.
Yes, you can contact American Regent Animal Health directly at 800-458-0163. You can also connect with your ARAH sales representative or contact your local distributor.
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