Multimodal therapy helps dogs live their most active lives

No matter how old a dog is, you can recommend a personalized plan to help preserve their joint health, so they can enjoy a lifetime of everyday adventures.

Adequan Canine can be a key component of your multimodal approach to treating dogs with arthritis:

Treatment with Adequan® Canine (polysulfated glycosaminoglycan) to protect and restore cartilage in the dog's synovial joints.

NSAIDs to help manage the pain and inflammation associated with canine osteoarthritis.

Adjunct therapy such as physical, laser, or heat/ice therapy to relieve soreness and stiffness.

Weight control through a healthy diet and exercise to keep dogs active and moving.

Joint supplements to promote overall joint health.

Nothing works like Adequan Canine

Adequan Canine is a joint-focused drug that actively treats arthritis and reduces pain and inflammation, which may lead to increased activity in dogs experiencing mobility issues.

Polysulfated glycosaminoglycan is the active ingredient in Adequan Canine. It works differently by binding to the cartilage matrix to help slow further degradation of the joints. The specific mechanism of action of Adequan® in canine joints is not known.

Here’s a proactive approach to managing arthritis with Adequan Canine
to help improve a dog’s mobility over their lifetime:

Make mobility a vital sign

  • Ask dog owners about changes in their dog’s activity level or movement
  • Share educational resources to help dog owners know what to look for

Start treatment early

  • Use a multimodal approach to support a dog’s overall joint health for the long haul
  • Prescribe Adequan Canine when you first identify a dog has arthritis

Proactively monitor joint health

  • Check in with dog owners at each appointment to monitor their dog’s mobility over time
  • Adjust the dog’s treatment plan to maximize the healthy benefits as they age

Repeat treatment with Adequan Canine

The specific mechanism of action of Adequan® in canine joints is not known.
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Adequan® Canine polysulfated glycosaminoglycan (PSGAG) solution 100 mg/mL

Adequan® Canine is recommended for intramuscular injection for the control of signs associated with non-infectious degenerative and/or traumatic arthritis of canine synovial joints.

Adequan® Canine should not be used in dogs who are hypersensitive to PSGAG or who have a known or suspected bleeding disorder. It should be used with caution in dogs with renal or hepatic impairment. Adverse reactions in clinical studies (transient pain at injection site, transient diarrhea, and abnormal bleeding) were mild and self-limiting. In post approval experience, death has been reported in some cases; vomiting, anorexia, depression/lethargy and diarrhea have also been reported. The safe use of PSGAG in breeding, pregnant or lactating dogs has not been evaluated. Caution: Federal law restricts this drug to use by or on the order of a licensed veterinarian. For additional safety information, please see full prescribing information.

Why multimodal treatment?


Get resources to support your recommendation

Check out our library of resources for handy tools to facilitate your conversations with dog owners about their dog’s mobility.


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